The Utah Highway Patrol said roads were snowy and slick when an eastbound red Jeep Liberty collided with a red Honda C-RV on U.S. 40 in Daniels Canyon near milepost 34.
The Jeep crossed the undivided median and hit the C-RV head-on.
Five people went to the hospital. A passenger in the C-RV was in critical condition. Four others had non-life-threatening injuries.
Crews cleared the crash and reopened westbound lanes around noon Nov. 5.